* Sergent Gary "Roach" Sanderson: Nolan North
* Løjtnant Simon "Ghost" Riley: Craig Fairbrass
* Major General Shepherd: Lance Henriksen
* Vladimir Makarov: Roman Varshavsky
* Yuri: Brian Bloom
* Alejandro Rojas: Gustavo Santaolalla
* Farah Karim: Claudia Doumit
* Victor Zakhaev: David Sobolov
* Pris: Barry Sloane