- Newbery Honor Award for "Judy Moody and the Not Bummer Summer" (2011)
- Theodor Seuss Geisel Honor Award for "Stink and the Ultimate Showdown" (2009)
- California Young Reader Medal for "Judy Moody and the Not Bummer Summer" (2012)
- Rhode Island Children's Book Award for "Judy Moody and the Not Bummer Summer" (2012)
- Georgia Children's Book Award for "Judy Moody and the Not Bummer Summer" (2013)
- Iowa Children's Choice Award for "Judy Moody and the Not Bummer Summer" (2013)
- Keystone State Reading Association Children's Book Award for "Judy Moody and the Not Bummer Summer" (2013)
Ud over disse er Megan McDonald også blevet anerkendt af American Library Association, Society of Children's Book Writers and Illustrators og National Education Association for sine bidrag til børnelitteratur.